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Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture

Glucagon-like peptide-1 (GLP-1) from intestinal L-cells stimulates insulin secretion and reduces appetite after food ingestion, and it is the basis for drugs against type-2 diabetes and obesity. Drugs targeting L- and other enteroendocrine cells are under development, with the aim to mimic endocrine...

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Detalles Bibliográficos
Autores principales:	Goldspink, Deborah A., Lu, Van B., Miedzybrodzka, Emily L., Smith, Christopher A., Foreman, Rachel E., Billing, Lawrence J., Kay, Richard G., Reimann, Frank, Gribble, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342002/ https://www.ncbi.nlm.nih.gov/pubmed/32610134 http://dx.doi.org/10.1016/j.celrep.2020.107833

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