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慢病毒介导的RNA干扰下调TSC2表达对白血病U937细胞系的影响及作用机制
OBJECTIVE: To investigate the effect of biology and mTOR pathway activity of down-regulated TSC2 gene expression on U937 leukemia cells. METHODS: Gene expression was down-regulated by lentivirus induced RNA interference on TSC2 high expressed U937 cell line; the proliferation, apoptosis and differen...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342282/ https://www.ncbi.nlm.nih.gov/pubmed/28810331 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.07.012 |