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Helicobacter pylori CagA Protein Attenuates 5-Fu Sensitivity of Gastric Cancer Cells Through Upregulating Cellular Glucose Metabolism

INTRODUCTION: Gastric cancer (GC) is one of the most malignancies leading to human mortality due to its development, progress, metastasis and poor prognosis, despite the development of remarkable chemotherapy and surgery. The 5-fluorouracil (5-Fu) is an effective anti-gastric cancer agent. However, a...

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Detalles Bibliográficos
Autores principales: Gao, Sujie, Song, Defeng, Liu, Yiting, Yan, Hongwei, Chen, Xuebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342331/
https://www.ncbi.nlm.nih.gov/pubmed/32753880
http://dx.doi.org/10.2147/OTT.S230875