Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice

Global pandemic of COVID-19 is a serious unmet medical need requiring clinical research into effective therapies. Clinical trials during pandemics of infections face complex challenges of putting scientific and ethical principles into practice. Some of these issues – selection of investigational pro...

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Detalles Bibliográficos
Autor principal: Bhatt, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342332/
https://www.ncbi.nlm.nih.gov/pubmed/32670829
http://dx.doi.org/10.4103/picr.PICR_77_20
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author Bhatt, Arun
author_facet Bhatt, Arun
author_sort Bhatt, Arun
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description Global pandemic of COVID-19 is a serious unmet medical need requiring clinical research into effective therapies. Clinical trials during pandemics of infections face complex challenges of putting scientific and ethical principles into practice. Some of these issues – selection of investigational product and participants, study design, assessment of efficacy and safety, ethics review, informed consent and publication, sample size, and publications – require in-depth consideration in planning and implementation of clinical trials during pandemics.
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spelling pubmed-73423322020-07-14 Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice Bhatt, Arun Perspect Clin Res Opinion Global pandemic of COVID-19 is a serious unmet medical need requiring clinical research into effective therapies. Clinical trials during pandemics of infections face complex challenges of putting scientific and ethical principles into practice. Some of these issues – selection of investigational product and participants, study design, assessment of efficacy and safety, ethics review, informed consent and publication, sample size, and publications – require in-depth consideration in planning and implementation of clinical trials during pandemics. Wolters Kluwer - Medknow 2020 2020-05-06 /pmc/articles/PMC7342332/ /pubmed/32670829 http://dx.doi.org/10.4103/picr.PICR_77_20 Text en Copyright: © 2020 Perspectives in Clinical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Opinion
Bhatt, Arun
Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title_full Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title_fullStr Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title_full_unstemmed Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title_short Clinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
title_sort clinical trials during the covid-19 pandemic: challenges of putting scientific and ethical principles into practice
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342332/
https://www.ncbi.nlm.nih.gov/pubmed/32670829
http://dx.doi.org/10.4103/picr.PICR_77_20
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