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CD19 CAR-T细胞培养过程中PD-1蛋白、mRNA水平及细胞杀伤活性变化
OBJECTIVE: To observe the changes of PD-1 expression, mRNA level and cytotoxic activity of CD19 CAR-T cells during the culture process of CAR-T cells. METHODS: The peripheral blood T cells of 6 lymphoma patients with high expression of PD-1 and 6 healthy volunteers were the source of CAR-T cells. Th...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342444/ https://www.ncbi.nlm.nih.gov/pubmed/31648479 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.09.010 |