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新酪氨酸激酶抑制剂BGJ398对白血病细胞株KG-1细胞的抑制效应研究
OBJECTIVE: To explore the effects and possible mechanisms of the novel pan-FGFR inhibitor BGJ398 on KG-1 cells in vitro. METHODS: Effects of BGJ398 on cells proliferation were detected by CCK-8, the apoptosis was assessed by Annexin V-FITC. Reverse transcriptionquantitative polymerase chain reaction...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342572/ https://www.ncbi.nlm.nih.gov/pubmed/29562450 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.02.013 |