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RNA腺苷脱氨酶在MLL-AF9诱导的小鼠急性髓系白血病发病中的作用
OBJECTIVE: To establish the ADAR1 (adenosine deaminase that act on RNA 1) knockout MLL-AF9 acute myeloid leukemia (AML) mouse model, and to preliminarily investigate the effects of ADAR1 deletion on the development of AML. METHODS: The lineage(−)(Lin(−)) cells of ER-CreADAR1(lox/lox) mice and their...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342600/ https://www.ncbi.nlm.nih.gov/pubmed/26031523 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.05.006 |