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CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习
OBJECTIVE: Presenting the clinical features of one patient with CD4(+)/CD8(−)T-cell large granular lymphocytic leukemia, to improve the understanding of the disease. METHODS: Clinical data of one patient hospitalized for skin rush and leukocytosis were analyzed, and the related literatures were revi...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
Editorial office of Chinese Journal of Hematology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342710/ https://www.ncbi.nlm.nih.gov/pubmed/26462772 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.09.004 |
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collection | PubMed |
description | OBJECTIVE: Presenting the clinical features of one patient with CD4(+)/CD8(−)T-cell large granular lymphocytic leukemia, to improve the understanding of the disease. METHODS: Clinical data of one patient hospitalized for skin rush and leukocytosis were analyzed, and the related literatures were reviewed. RESULTS: The patient was hospitalized for skin rush and leukocytosis. Routine blood test showed remarkable elevated white blood cell counts and mild anemia. Subsequent hematological examination led to a diagnosis of T-cell large granular lymphocytic leukemia with CD4 (+)/CD8(−)immunophenontype. CONCLUSION: CD3 (+)/CD4(+)/CD8(−)T-cell large granular lymphocytic leukemia is a kind of variant subtype, and is relatively rare, it has different clinical features with classic CD3(+)/CD4(−)/CD8(+)/TCRαβ(+) T-cell large granular lymphocytic leukemia, so differentiating diagnosis is of great importance. |
format | Online Article Text |
id | pubmed-7342710 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Editorial office of Chinese Journal of Hematology |
record_format | MEDLINE/PubMed |
spelling | pubmed-73427102020-07-16 CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 Zhonghua Xue Ye Xue Za Zhi 论著 OBJECTIVE: Presenting the clinical features of one patient with CD4(+)/CD8(−)T-cell large granular lymphocytic leukemia, to improve the understanding of the disease. METHODS: Clinical data of one patient hospitalized for skin rush and leukocytosis were analyzed, and the related literatures were reviewed. RESULTS: The patient was hospitalized for skin rush and leukocytosis. Routine blood test showed remarkable elevated white blood cell counts and mild anemia. Subsequent hematological examination led to a diagnosis of T-cell large granular lymphocytic leukemia with CD4 (+)/CD8(−)immunophenontype. CONCLUSION: CD3 (+)/CD4(+)/CD8(−)T-cell large granular lymphocytic leukemia is a kind of variant subtype, and is relatively rare, it has different clinical features with classic CD3(+)/CD4(−)/CD8(+)/TCRαβ(+) T-cell large granular lymphocytic leukemia, so differentiating diagnosis is of great importance. Editorial office of Chinese Journal of Hematology 2015-09 /pmc/articles/PMC7342710/ /pubmed/26462772 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.09.004 Text en 2015年版权归中华医学会所有 http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution 3.0 License (CC-BY-NC). The Copyright own by Publisher. Without authorization, shall not reprint, except this publication article, shall not use this publication format design. Unless otherwise stated, all articles published in this journal do not represent the views of the Chinese Medical Association or the editorial board of this journal. |
spellingShingle | 论著 CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title | CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title_full | CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title_fullStr | CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title_full_unstemmed | CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title_short | CD4(+)/CD8(−)T-大颗粒淋巴细胞白血病一例报告并文献复习 |
title_sort | cd4(+)/cd8(−)t-大颗粒淋巴细胞白血病一例报告并文献复习 |
topic | 论著 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342710/ https://www.ncbi.nlm.nih.gov/pubmed/26462772 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.09.004 |
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