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雷帕霉素对重型再生障碍性贫血模型小鼠脾脏CD4(+)CD25(+) T细胞凋亡的影响
OBJECTIVE: To explore the effects and possible mechanism of rapamycin (RAPA) on apoptosis of CD4(+)CD25(+) Tregs from the mouse severe aplastic anemia (SAA) model. METHODS: The BALB/c female SAA model mice were induced by interferon-gamma in combination with busulphan. The SAA model mice were intrap...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342986/ https://www.ncbi.nlm.nih.gov/pubmed/29562463 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.03.005 |