Model-Based Approach for Establishing the Predicted Clinical Response of a Delayed-Release and Extended-Release Methylphenidate for the Treatment of Attention-Deficit/Hyperactivity Disorder

PURPOSE/BACKGROUND: HLD200 is an evening-dosed, delayed-release and extended-release methylphenidate (DR/ER-MPH) that provides a consistent delay in initial drug release to target onset of therapeutic effect from awakening and maintain it into the evening. Building on a modeling framework establishe...

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Detalles Bibliográficos
Autores principales: Gomeni, Roberto, Komolova, Marina, Incledon, Bev, Faraone, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343180/
https://www.ncbi.nlm.nih.gov/pubmed/32590405
http://dx.doi.org/10.1097/JCP.0000000000001222

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