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Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection

While the relationship of protective human leukocyte antigen (HLA) class I alleles and HIV progression is well defined, the interaction of HLA-mediated protection and CD8 T-cell exhaustion is less well characterized. To gain insight into the influence of HLA-B*57:01 on the deterioration of CD8 T-cel...

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Detalles Bibliográficos
Autores principales:	Scharf, Lydia, Tauriainen, Johanna, Buggert, Marcus, Hartogensis, Wendy, Nolan, David J., Deeks, Steven G., Salemi, Marco, Hecht, Frederick M., Karlsson, Annika C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343205/ https://www.ncbi.nlm.nih.gov/pubmed/32350076 http://dx.doi.org/10.1128/JVI.02128-19

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