MiR-7 Functions as a Tumor Suppressor by Targeting the Oncogenes TAL1 in T-Cell Acute Lymphoblastic Leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia is a hematologic malignancy characterized by T-cell proliferation, and in many cases, the ectopic expression of the oncogenic transcription factor T-cell acute lymphocytic leukemia protein 1 (TAL1). MicroRNA-7 has been shown to play a critical role in...

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Detalles Bibliográficos
Autores principales: Sun, Hongbo, Zhang, Zhifu, Luo, Wei, Liu, Junmin, Lou, Ye, Xia, Shengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343363/
https://www.ncbi.nlm.nih.gov/pubmed/32633635
http://dx.doi.org/10.1177/1533033820934130