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De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

The outbreak of COVID-19 has now become a global pandemic that has severely impacted lives and economic stability. There is, however, no effective antiviral drug that can be used to treat COVID-19 to date. Built on the fact that SARS-CoV-2 initiates its entry into human cells by the receptor binding...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343451/
https://www.ncbi.nlm.nih.gov/pubmed/32544884
http://dx.doi.org/10.18632/aging.103416