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Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer

CD8(+) tumor-infiltrating lymphocytes (TILs) are not all specific for tumor antigens, but can include bystander TILs that are specific for cancer-irrelevant epitopes, and it is unknown whether the T-cell repertoire affects prognosis. To delineate the complexity of anti-tumor T-cell responses, we uti...

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Detalles Bibliográficos
Autores principales:	Tsuji, Takemasa, Eng, Kevin H., Matsuzaki, Junko, Battaglia, Sebastiano, Szender, J. Brian, Miliotto, Anthony, Gnjatic, Sacha, Bshara, Wiam, Morrison, Carl D., Lele, Shashikant, Emerson, Ryan O., Wang, Jianmin, Liu, Song, Robins, Harlan, Lugade, Amit A., Odunsi, Kunle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343634/ https://www.ncbi.nlm.nih.gov/pubmed/32676168 http://dx.doi.org/10.18632/oncotarget.27666

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