Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis

BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) begins with steatosis, where a mixed macrovesicular pattern of large and small lipid droplets (LDs) develops. Since in vitro models recapitulating this are limited, the aims of this study were to develop mixed macrovesicular steatosis in...

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Detalles Bibliográficos
Autores principales: Gunn, Pippa J., Pramfalk, Camilla, Millar, Val, Cornfield, Thomas, Hutchinson, Matthew, Johnson, Elspeth M., Nagarajan, Shilpa R., Troncoso‐Rey, Perla, Mithen, Richard F., Pinnick, Katherine E., Traka, Maria H., Green, Charlotte J., Hodson, Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343665/
https://www.ncbi.nlm.nih.gov/pubmed/32643289
http://dx.doi.org/10.14814/phy2.14482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343665/
https://www.ncbi.nlm.nih.gov/pubmed/32643289
http://dx.doi.org/10.14814/phy2.14482

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