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Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis

Macrophage activation involves metabolic reprogramming to support antimicrobial cellular functions. How these metabolic shifts influence the outcome of infection by intracellular pathogens remains incompletely understood. Mycobacterium tuberculosis (Mtb) modulates host metabolic pathways and utilize...

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Detalles Bibliográficos
Autores principales: Chandra, Pallavi, He, Li, Zimmerman, Matthew, Yang, Guozhe, Köster, Stefan, Ouimet, Mireille, Wang, Han, Moore, Kathyrn J., Dartois, Véronique, Schilling, Joel D., Philips, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343992/
https://www.ncbi.nlm.nih.gov/pubmed/32636249
http://dx.doi.org/10.1128/mBio.01139-20

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