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Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis
Macrophage activation involves metabolic reprogramming to support antimicrobial cellular functions. How these metabolic shifts influence the outcome of infection by intracellular pathogens remains incompletely understood. Mycobacterium tuberculosis (Mtb) modulates host metabolic pathways and utilize...
Autores principales: | Chandra, Pallavi, He, Li, Zimmerman, Matthew, Yang, Guozhe, Köster, Stefan, Ouimet, Mireille, Wang, Han, Moore, Kathyrn J., Dartois, Véronique, Schilling, Joel D., Philips, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343992/ https://www.ncbi.nlm.nih.gov/pubmed/32636249 http://dx.doi.org/10.1128/mBio.01139-20 |
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