Cargando…

Apoptin Regulates Apoptosis and Autophagy by Modulating Reactive Oxygen Species (ROS) Levels in Human Liver Cancer Cells

Apoptin is a protein that specifically induces apoptosis in tumor cells. The anti-tumorigenic functions of Apoptin, including autophagy activation and its interaction with apoptosis, have not been precisely elucidated. Here we investigate the main pathways of apoptin-mediated killing of human liver...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yiquan, Zhu, Yilong, Fang, Jinbo, Li, Wenjie, Li, Shanzhi, Liu, Xing, Liu, Zirui, Song, Gaojie, Shang, Chao, Cong, Jianan, Bai, Bing, Sun, Lili, Jin, Ningyi, Li, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344208/ https://www.ncbi.nlm.nih.gov/pubmed/32714864 http://dx.doi.org/10.3389/fonc.2020.01026

Ejemplares similares

Apoptin mediates mitophagy and endogenous apoptosis by regulating the level of ROS in hepatocellular carcinoma
por: Li, Yiquan, et al.
Publicado: (2022)

Effects of Apoptin-Induced Endoplasmic Reticulum Stress on Lipid Metabolism, Migration, and Invasion of HepG-2 Cells
por: Zhu, Yilong, et al.
Publicado: (2021)

Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway
por: Liu, Zirui, et al.
Publicado: (2022)

Ad-Apoptin-hTERTp-E1a Regulates Autophagy Through the AMPK-mTOR-eIF4F Signaling Axis to Reduce Drug Resistance of MCF-7/ADR Cells
por: Li, Yaru, et al.
Publicado: (2021)

Apoptin causes apoptosis in HepG‐2 cells via Ca(2+) imbalance and activation of the mitochondrial apoptotic pathway
por: Yu, Xiaoyang, et al.
Publicado: (2022)

Anti‐tumour effects of a dual cancer‐specific oncolytic adenovirus on Breast Cancer Stem cells
por: Li, Wenjie, et al.
Publicado: (2020)

Chemovirotherapy of Lung Squamous Cell Carcinoma by Combining Oncolytic Adenovirus With Gemcitabine
por: Liu, Xing, et al.
Publicado: (2020)

Ad-VT enhances the sensitivity of chemotherapy-resistant lung adenocarcinoma cells to gemcitabine and paclitaxel in vitro and in vivo
por: Song, Gaojie, et al.
Publicado: (2022)

Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro
por: Xiu, Zhiru, et al.
Publicado: (2023)

A comparative study of the ability of recombinant oncolytic adenovirus, doxorubicin and tamoxifen to inhibit the proliferation of breast cancer cells
por: Li, Shanzhi, et al.
Publicado: (2022)

Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma
por: Xiu, Zhiru, et al.
Publicado: (2022)

Anti-tumor Synergistic Effect of a Dual Cancer-Specific Recombinant Adenovirus and Paclitaxel on Breast Cancer
por: Wang, Jing, et al.
Publicado: (2020)

Generation of an Attenuated Tiantan Vaccinia Virus Strain by Deletion of Multiple Genes
por: Li, Yiquan, et al.
Publicado: (2017)

Inhibition of Autophagy Suppresses SARS-CoV-2 Replication and Ameliorates Pneumonia in hACE2 Transgenic Mice and Xenografted Human Lung Tissues
por: Shang, Chao, et al.
Publicado: (2021)

Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo
por: Xiao, Li, et al.
Publicado: (2010)

Human adenovirus type 7 subunit vaccine induces dendritic cell maturation through the TLR4/NF-κB pathway is highly immunogenic
por: Li, Yaru, et al.
Publicado: (2023)

Mapping of Apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy
por: Jangamreddy, Jaganmohan R., et al.
Publicado: (2014)

A peptide derived from apoptin inhibits glioma growth
por: Zhang, Liqiu, et al.
Publicado: (2017)

Recombinant adenoviruses expressing apoptin suppress the growth of MCF-7 breast cancer cells and affect cell autophagy
por: Chen, Shuang, et al.
Publicado: (2019)

SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment
por: Shang, Chao, et al.
Publicado: (2022)

Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice
por: Shang, Chao, et al.
Publicado: (2021)

Salmonella typhimurium Mediated Delivery of Apoptin in Human Laryngeal Cancer
por: Guan, Guo-fang, et al.
Publicado: (2013)

The Role of Apoptin in Chicken Anemia Virus Replication
por: Feng, Cynthia, et al.
Publicado: (2020)

VP2 of Chicken Anaemia Virus Interacts with Apoptin for Down-regulation of Apoptosis through De-phosphorylated Threonine 108 on Apoptin
por: Lai, Guan-Hua, et al.
Publicado: (2017)

Bafilomycin A1 inhibits SARS-CoV-2 infection in a human lung xenograft mouse model
por: Zhang, Cuiling, et al.
Publicado: (2023)

Synergistic antitumor effect of the combination of a dual cancer-specific oncolytic adenovirus and cisplatin on lung cancer cells
por: Jin, Jing, et al.
Publicado: (2018)

Human Gyrovirus Apoptin shows a similar subcellular distribution pattern and apoptosis induction as the chicken anaemia virus derived VP3/Apoptin
por: Bullenkamp, J, et al.
Publicado: (2012)

URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells
por: Xu, Yue, et al.
Publicado: (2021)

Rasfonin promotes autophagy and apoptosis via upregulation of reactive oxygen species (ROS)/JNK pathway
por: Wang, Weijun, et al.
Publicado: (2016)

C-terminal region of apoptin affects chicken anemia virus replication and virulence
por: Wang, Yongqiang, et al.
Publicado: (2017)

Human serum albumin-mediated apoptin delivery suppresses breast cancer cell growth in vitro and in vivo
por: Wu, Fang, et al.
Publicado: (2017)

Apoptotic and autophagic cell death induced in cervical cancer cells by a dual specific oncolytic adenovirus
por: Li, Shanzhi, et al.
Publicado: (2022)

Myricetin activates the Caspase-3/GSDME pathway via ER stress induction of pyroptosis in lung cancer cells
por: Han, Jicheng, et al.
Publicado: (2022)

Deconvoluting the Complexity of Reactive Oxygen Species (ROS) in Neurodegenerative Diseases
por: Zhou, Yuxin, et al.
Publicado: (2022)

Recombinant Oncolytic Adenovirus Combined with Cyclophosphamide Induces Synergy in the Treatment of Breast Cancer in vitro and in vivo
por: Wang, Jing, et al.
Publicado: (2022)

The Role of Reactive Oxygen Species and Autophagy in Periodontitis and Their Potential Linkage
por: Liu, Chengcheng, et al.
Publicado: (2017)

Reactive Oxygen Species (ROS)-Responsive Nanomedicine for Solving Ischemia-Reperfusion Injury
por: Chen, Weiyu, et al.
Publicado: (2020)

Mitotic catastrophe triggered in human cancer cells by the viral protein apoptin
por: Lanz, H L, et al.
Publicado: (2013)

Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and targeting therapy of osteoarthritis
por: Shen, Chong, et al.
Publicado: (2021)

Role of ROS-mediated autophagy in melanoma
por: Zhang, Xuebing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oisbt2e2mg385c9180lns2utd4