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HCV Replicon Systems: Workhorses of Drug Discovery and Resistance

The development of direct-acting antivirals (DAAs) has revolutionized the state-of-the art treatment of HCV infections, with sustained virologic response rates above 90%. However, viral variants harboring substitutions referred to as resistance-associated substitutions (RASs) may be present in basel...

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Detalles Bibliográficos
Autores principales: Khan, Shaheen, Soni, Shalini, Veerapu, Naga Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344236/
https://www.ncbi.nlm.nih.gov/pubmed/32714881
http://dx.doi.org/10.3389/fcimb.2020.00325