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Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington

IMPORTANCE: The ability to identify patients with coronavirus disease 2019 (COVID-19) in the prehospital emergency setting could inform strategies for infection control and use of personal protective equipment. However, little is known about the presentation of patients with COVID-19 requiring emerg...

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Autores principales: Yang, Betty Y., Barnard, Leslie M., Emert, Jamie M., Drucker, Christopher, Schwarcz, Leilani, Counts, Catherine R., Murphy, David L., Guan, Sally, Kume, Kosuke, Rodriquez, Karen, Jacinto, Tracie, May, Susanne, Sayre, Michael R., Rea, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344378/
https://www.ncbi.nlm.nih.gov/pubmed/32639570
http://dx.doi.org/10.1001/jamanetworkopen.2020.14549
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author Yang, Betty Y.
Barnard, Leslie M.
Emert, Jamie M.
Drucker, Christopher
Schwarcz, Leilani
Counts, Catherine R.
Murphy, David L.
Guan, Sally
Kume, Kosuke
Rodriquez, Karen
Jacinto, Tracie
May, Susanne
Sayre, Michael R.
Rea, Thomas
author_facet Yang, Betty Y.
Barnard, Leslie M.
Emert, Jamie M.
Drucker, Christopher
Schwarcz, Leilani
Counts, Catherine R.
Murphy, David L.
Guan, Sally
Kume, Kosuke
Rodriquez, Karen
Jacinto, Tracie
May, Susanne
Sayre, Michael R.
Rea, Thomas
author_sort Yang, Betty Y.
collection PubMed
description IMPORTANCE: The ability to identify patients with coronavirus disease 2019 (COVID-19) in the prehospital emergency setting could inform strategies for infection control and use of personal protective equipment. However, little is known about the presentation of patients with COVID-19 requiring emergency care, particularly those who used 911 emergency medical services (EMS). OBJECTIVE: To describe patient characteristics and prehospital presentation of patients with COVID-19 cared for by EMS. DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included 124 patients who required 911 EMS care for COVID-19 in King County, Washington, a large metropolitan region covering 2300 square miles with 2.2 million residents in urban, suburban, and rural areas, between February 1, 2020, and March 18, 2020. EXPOSURES: COVID-19 was diagnosed by reverse transcription–polymerase chain reaction detection of severe acute respiratory syndrome coronavirus 2 from nasopharyngeal swabs. Test results were available a median (interquartile range) of 5 (3-9) days after the EMS encounter. MAIN OUTCOMES AND MEASURES: Prevalence of clinical characteristics, symptoms, examination signs, and EMS impression and care. RESULTS: Of the 775 confirmed COVID-19 cases in King County, EMS responded to 124 (16.0%), with a total of 147 unique 911 encounters. The mean (SD) age was 75.7 (13.2) years, 66 patients (53.2%) were women, 47 patients (37.9%) had 3 or more chronic health conditions, and 57 patients (46.0%) resided in a long-term care facility. Based on EMS evaluation, 43 of 147 encounters (29.3%) had no symptoms of fever, cough, or shortness of breath. Based on individual examination findings, fever, tachypnea, or hypoxia were only present in a limited portion of cases, as follows: 43 of 84 encounters (51.2%), 42 of 131 (32.1%), and 60 of 112 (53.6%), respectively. Advanced care was typically not required, although in 24 encounters (16.3%), patients received care associated with aerosol-generating procedures. As of June 1, 2020, mortality among the study cohort was 52.4% (65 patients). CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that screening based on conventional COVID-19 symptoms or corresponding examination findings of febrile respiratory illness may not possess the necessary sensitivity for early diagnostic suspicion, at least in the prehospital emergency setting. The findings have potential implications for early identification of COVID-19 and effective strategies to mitigate infectious risk during emergency care.
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spelling pubmed-73443782020-07-13 Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington Yang, Betty Y. Barnard, Leslie M. Emert, Jamie M. Drucker, Christopher Schwarcz, Leilani Counts, Catherine R. Murphy, David L. Guan, Sally Kume, Kosuke Rodriquez, Karen Jacinto, Tracie May, Susanne Sayre, Michael R. Rea, Thomas JAMA Netw Open Original Investigation IMPORTANCE: The ability to identify patients with coronavirus disease 2019 (COVID-19) in the prehospital emergency setting could inform strategies for infection control and use of personal protective equipment. However, little is known about the presentation of patients with COVID-19 requiring emergency care, particularly those who used 911 emergency medical services (EMS). OBJECTIVE: To describe patient characteristics and prehospital presentation of patients with COVID-19 cared for by EMS. DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included 124 patients who required 911 EMS care for COVID-19 in King County, Washington, a large metropolitan region covering 2300 square miles with 2.2 million residents in urban, suburban, and rural areas, between February 1, 2020, and March 18, 2020. EXPOSURES: COVID-19 was diagnosed by reverse transcription–polymerase chain reaction detection of severe acute respiratory syndrome coronavirus 2 from nasopharyngeal swabs. Test results were available a median (interquartile range) of 5 (3-9) days after the EMS encounter. MAIN OUTCOMES AND MEASURES: Prevalence of clinical characteristics, symptoms, examination signs, and EMS impression and care. RESULTS: Of the 775 confirmed COVID-19 cases in King County, EMS responded to 124 (16.0%), with a total of 147 unique 911 encounters. The mean (SD) age was 75.7 (13.2) years, 66 patients (53.2%) were women, 47 patients (37.9%) had 3 or more chronic health conditions, and 57 patients (46.0%) resided in a long-term care facility. Based on EMS evaluation, 43 of 147 encounters (29.3%) had no symptoms of fever, cough, or shortness of breath. Based on individual examination findings, fever, tachypnea, or hypoxia were only present in a limited portion of cases, as follows: 43 of 84 encounters (51.2%), 42 of 131 (32.1%), and 60 of 112 (53.6%), respectively. Advanced care was typically not required, although in 24 encounters (16.3%), patients received care associated with aerosol-generating procedures. As of June 1, 2020, mortality among the study cohort was 52.4% (65 patients). CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that screening based on conventional COVID-19 symptoms or corresponding examination findings of febrile respiratory illness may not possess the necessary sensitivity for early diagnostic suspicion, at least in the prehospital emergency setting. The findings have potential implications for early identification of COVID-19 and effective strategies to mitigate infectious risk during emergency care. American Medical Association 2020-07-08 /pmc/articles/PMC7344378/ /pubmed/32639570 http://dx.doi.org/10.1001/jamanetworkopen.2020.14549 Text en Copyright 2020 Yang BY et al. JAMA Network Open. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the CC-BY License.
spellingShingle Original Investigation
Yang, Betty Y.
Barnard, Leslie M.
Emert, Jamie M.
Drucker, Christopher
Schwarcz, Leilani
Counts, Catherine R.
Murphy, David L.
Guan, Sally
Kume, Kosuke
Rodriquez, Karen
Jacinto, Tracie
May, Susanne
Sayre, Michael R.
Rea, Thomas
Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title_full Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title_fullStr Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title_full_unstemmed Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title_short Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington
title_sort clinical characteristics of patients with coronavirus disease 2019 (covid-19) receiving emergency medical services in king county, washington
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344378/
https://www.ncbi.nlm.nih.gov/pubmed/32639570
http://dx.doi.org/10.1001/jamanetworkopen.2020.14549
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