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Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding

There is evidence that preterm infants of migrant mothers are at a higher risk of adverse perinatal outcomes than those of native-born mothers, and that human milk feeding is beneficial to infants’ neurodevelopment. Using the United Nations Human Development Index (HDI) to classify mother’s country...

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Autores principales: Gibertoni, Dino, Sansavini, Alessandra, Savini, Silvia, Locatelli, Chiara, Ancora, Gina, Perrone, Enrica, Ialonardi, Magda, Rucci, Paola, Fantini, Maria Pia, Faldella, Giacomo, Corvaglia, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344423/
https://www.ncbi.nlm.nih.gov/pubmed/32630587
http://dx.doi.org/10.3390/ijerph17124588
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author Gibertoni, Dino
Sansavini, Alessandra
Savini, Silvia
Locatelli, Chiara
Ancora, Gina
Perrone, Enrica
Ialonardi, Magda
Rucci, Paola
Fantini, Maria Pia
Faldella, Giacomo
Corvaglia, Luigi
author_facet Gibertoni, Dino
Sansavini, Alessandra
Savini, Silvia
Locatelli, Chiara
Ancora, Gina
Perrone, Enrica
Ialonardi, Magda
Rucci, Paola
Fantini, Maria Pia
Faldella, Giacomo
Corvaglia, Luigi
author_sort Gibertoni, Dino
collection PubMed
description There is evidence that preterm infants of migrant mothers are at a higher risk of adverse perinatal outcomes than those of native-born mothers, and that human milk feeding is beneficial to infants’ neurodevelopment. Using the United Nations Human Development Index (HDI) to classify mother’s country of origin, we investigated whether type of neonatal feeding (human milk vs. mixed milk vs. exclusive formula milk) affected preterm newborn neurodevelopment varying across different HDI categories (Italian native-born vs. high HDI migrant vs. low HDI migrant) up to 2 years of age. Neurodevelopment of 530 infants born in Italy at ≤32 weeks of gestational age and/or weighing <1500 g was measured at 3-, 6-, 9-, 12-, 18-, and 24-months corrected age (CA) using the revised Griffiths Mental Development Scale 0–2 years. The trajectories of the general developmental quotient and its five subscales were estimated using mixed models. At 24-months CA only preterm infants of low HDI migrant mothers and fed exclusive formula milk showed moderate neurodevelopment impairment, with lower developmental trajectories of eye-hand coordination, performance, and personal-social abilities. Migrant mothers from low HDI countries and their preterm infants should be targeted by specific programs supporting maternal environment, infant development, and human or mixed milk neonatal feeding. Future research should focus on a deeper understanding of the mechanisms through which type of feeding and mother migrant conditions interact in influencing preterm infants’ neurodevelopment.
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spelling pubmed-73444232020-07-14 Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding Gibertoni, Dino Sansavini, Alessandra Savini, Silvia Locatelli, Chiara Ancora, Gina Perrone, Enrica Ialonardi, Magda Rucci, Paola Fantini, Maria Pia Faldella, Giacomo Corvaglia, Luigi Int J Environ Res Public Health Article There is evidence that preterm infants of migrant mothers are at a higher risk of adverse perinatal outcomes than those of native-born mothers, and that human milk feeding is beneficial to infants’ neurodevelopment. Using the United Nations Human Development Index (HDI) to classify mother’s country of origin, we investigated whether type of neonatal feeding (human milk vs. mixed milk vs. exclusive formula milk) affected preterm newborn neurodevelopment varying across different HDI categories (Italian native-born vs. high HDI migrant vs. low HDI migrant) up to 2 years of age. Neurodevelopment of 530 infants born in Italy at ≤32 weeks of gestational age and/or weighing <1500 g was measured at 3-, 6-, 9-, 12-, 18-, and 24-months corrected age (CA) using the revised Griffiths Mental Development Scale 0–2 years. The trajectories of the general developmental quotient and its five subscales were estimated using mixed models. At 24-months CA only preterm infants of low HDI migrant mothers and fed exclusive formula milk showed moderate neurodevelopment impairment, with lower developmental trajectories of eye-hand coordination, performance, and personal-social abilities. Migrant mothers from low HDI countries and their preterm infants should be targeted by specific programs supporting maternal environment, infant development, and human or mixed milk neonatal feeding. Future research should focus on a deeper understanding of the mechanisms through which type of feeding and mother migrant conditions interact in influencing preterm infants’ neurodevelopment. MDPI 2020-06-25 2020-06 /pmc/articles/PMC7344423/ /pubmed/32630587 http://dx.doi.org/10.3390/ijerph17124588 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gibertoni, Dino
Sansavini, Alessandra
Savini, Silvia
Locatelli, Chiara
Ancora, Gina
Perrone, Enrica
Ialonardi, Magda
Rucci, Paola
Fantini, Maria Pia
Faldella, Giacomo
Corvaglia, Luigi
Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title_full Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title_fullStr Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title_full_unstemmed Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title_short Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding
title_sort neurodevelopmental trajectories of preterm infants of italian native-born and migrant mothers and role of neonatal feeding
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344423/
https://www.ncbi.nlm.nih.gov/pubmed/32630587
http://dx.doi.org/10.3390/ijerph17124588
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