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Synergistic Effect of WTC-Particulate Matter and Lysophosphatidic Acid Exposure and the Role of RAGE: In-Vitro and Translational Assessment
World Trade Center particulate matter (WTC-PM)-exposed firefighters with metabolic syndrome (MetSyn) have a higher risk of WTC lung injury (WTC-LI). Since macrophages are crucial innate pulmonary mediators, we investigated WTC-PM/lysophosphatidic acid (LPA) co-exposure in macrophages. LPA, a low-den...
Autores principales: | Lam, Rachel, Haider, Syed H., Crowley, George, Caraher, Erin J., Ostrofsky, Dean F., Talusan, Angela, Kwon, Sophia, Prezant, David J., Wang, Yuyan, Liu, Mengling, Nolan, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344461/ https://www.ncbi.nlm.nih.gov/pubmed/32560330 http://dx.doi.org/10.3390/ijerph17124318 |
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