Cargando…

Exploring the Mechanism of Flaccidoxide-13-Acetate in Suppressing Cell Metastasis of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the most common liver or hepatic cancer, accounting for 80% of all cases. The majority of this cancer mortality is due to metastases, rather than orthotopic tumors. Therefore, the inhibition of tumor metastasis is widely recognized as the key strategy for successful...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yu-Jen, Wei, Wen-Chi, Dai, Guo-Fong, Su, Jui-Hsin, Tseng, Yu-Hwei, Tsai, Tsung-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344577/ https://www.ncbi.nlm.nih.gov/pubmed/32549236 http://dx.doi.org/10.3390/md18060314

Ejemplares similares

Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway
por: Wu, Yu-Jen, et al.
Publicado: (2019)

Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway
por: Neoh, Choo-Aun, et al.
Publicado: (2017)

11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways
por: Lin, Jen-Jie, et al.
Publicado: (2014)

Stellettin B Isolated from Stelletta Sp. Reduces Migration and Invasion of Hepatocellular Carcinoma Cells through Reducing Activation of the MAPKs and FAK/PI3K/AKT/mTOR Signaling Pathways
por: Tsai, Tsung-Chang, et al.
Publicado: (2022)

The Blockade of Mitogen-Activated Protein Kinase 14 Activation by Marine Natural Product Crassolide Triggers ICD in Tumor Cells and Stimulates Anti-Tumor Immunity
por: Tsai, Keng-Chang, et al.
Publicado: (2023)

De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells
por: Chang, Yi-Wen, et al.
Publicado: (2014)

13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway
por: Hsu, Chang-Min, et al.
Publicado: (2022)

Survival outcomes and prognostic factors for first-line abiraterone acetate or enzalutamide in patients with metastatic castration-resistant prostate cancer
por: Tseng, Chi-Shin, et al.
Publicado: (2023)

Regorafenib inhibits tumor progression through suppression of ERK/NF-κB activation in hepatocellular carcinoma bearing mice
por: Weng, Mao-Chi, et al.
Publicado: (2018)

Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways
por: Wu, Yu-Jen, et al.
Publicado: (2015)

Pelvic skeletal metastasis of hepatocellular carcinoma with sarcomatous change: a case report
por: Chen, Chih-Yu, et al.
Publicado: (2010)

Proton Beam Therapy in Managing Unresectable Hepatocellular Carcinoma with Bile Duct Invasion
por: Lee, Ching-Hsin, et al.
Publicado: (2022)

Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer
por: Yang, Chih-Jen, et al.
Publicado: (2015)

Licochalcone A Suppresses Renal Cancer Cell Proliferation and Metastasis by Engagement of Sp1-Mediated LC3 Expression
por: Tseng, Tsai-Yi, et al.
Publicado: (2023)

PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis
por: Chua, Huey-Huey, et al.
Publicado: (2022)

Sphingosine‐1‐phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR‐101 expression
por: Tsai, Chun‐Hao, et al.
Publicado: (2017)

Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinoma
por: Tseng, Yi-Hsin, et al.
Publicado: (2016)

Composite hepatocellular carcinoma and small cell carcinoma with early nodal metastasis: A case report
por: Liu, Yu-Jen, et al.
Publicado: (2017)

Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling
por: Yeh, Yu-Wen, et al.
Publicado: (2016)

An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells
por: Su, Ching-Chyuan, et al.
Publicado: (2011)

Glypican-3: A molecular marker for the detection and treatment of hepatocellular carcinoma(☆)
por: Shih, Tsung-Chieh, et al.
Publicado: (2020)

Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37
por: Tzeng, Hong-Tai, et al.
Publicado: (2017)

Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells
por: Ying, Tsung-Ho, et al.
Publicado: (2016)

A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados
por: Tsai, Tsung-Chang, et al.
Publicado: (2013)

7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway
por: Tsai, Tsung-Chang, et al.
Publicado: (2018)

Borneol and Tetrandrine Modulate the Blood–Brain Barrier and Blood–Tumor Barrier to Improve the Therapeutic Efficacy of 5-Fluorouracil in Brain Metastasis
por: Lin, Jui-Feng, et al.
Publicado: (2022)

A Soft Coral-Derived Compound, 11-epi-Sinulariolide Acetate Suppresses Inflammatory Response and Bone Destruction in Adjuvant-Induced Arthritis
por: Lin, Yen-You, et al.
Publicado: (2013)

Efficacy of Cyproheptadine Monotherapy in Hepatocellular Carcinoma With Bone Metastasis: A Case Report
por: Feng, Yu-Min, et al.
Publicado: (2021)

LPAL2 Suppresses Tumor Growth and Metastasis of Hepatocellular Carcinoma by Modulating MMP9 Expression
por: Lin, Yang-Hsiang, et al.
Publicado: (2022)

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4(+) T Lymphocytes
por: Tsai, Cheng-Chieh, et al.
Publicado: (2020)

Linalyl Acetate Ameliorates Mechanical Hyperalgesia Through Suppressing Inflammation by TSLP/IL-33 Signaling
por: Lu, Ying-Yi, et al.
Publicado: (2022)

13-Acetoxysarcocrassolide Induces Apoptosis on Human Gastric Carcinoma Cells Through Mitochondria-Related Apoptotic Pathways: p38/JNK Activation and PI3K/AKT Suppression
por: Su, Ching-Chyuan, et al.
Publicado: (2014)

Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2
por: Song, Dongqiang, et al.
Publicado: (2022)

Molecular mechanism of albumin in suppressing invasion and metastasis of hepatocellular carcinoma
por: Fu, Xiao, et al.
Publicado: (2021)

Identification of 13 Novel Loci in a Genome-Wide Association Study on Taiwanese with Hepatocellular Carcinoma
por: Liu, Ting-Yuan, et al.
Publicado: (2023)

Effects of Lactobacillus plantarum TWK10-Fermented Soymilk on Deoxycorticosterone Acetate-Salt-Induced Hypertension and Associated Dementia in Rats
por: Liu, Te-Hua, et al.
Publicado: (2016)

Effects of Black Garlic Extract and Nanoemulsion on the Deoxy Corticosterone Acetate-Salt Induced Hypertension and Its Associated Mild Cognitive Impairment in Rats
por: Chen, Chun-Yu, et al.
Publicado: (2021)

MMP-13 is involved in oral cancer cell metastasis
por: Huang, Shun-Hong, et al.
Publicado: (2016)

Exploring and Developing the Workplace Health Culture Scale in Taiwan
por: Chang, Yao-Tsung, et al.
Publicado: (2020)

Long Non-Coding RNA STARD13-AS Suppresses Cell Proliferation And Metastasis In Colorectal Cancer
por: Yang, Bin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t7jf6ral090u7curds7qalpv21