Cargando…

Effects of a Newly Developed Enzyme-Assisted Extraction Method on the Biological Activities of Fucoidans in Ocular Cells

Fucoidans from brown seaweeds are promising substances as potential drugs against age-related macular degeneration (AMD). The heterogeneity of fucoidans requires intensive research in order to find suitable species and extraction methods. Ten different fucoidan samples extracted enzymatically from L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dörschmann, Philipp, Mikkelsen, Maria Dalgaard, Thi, Thuan Nguyen, Roider, Johann, Meyer, Anne S., Klettner, Alexa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344579/ https://www.ncbi.nlm.nih.gov/pubmed/32466624 http://dx.doi.org/10.3390/md18060282

Ejemplares similares

Effects of Fucoidans from Five Different Brown Algae on Oxidative Stress and VEGF Interference in Ocular Cells
por: Dörschmann, Philipp, et al.
Publicado: (2019)

Interaction of High-Molecular Weight Fucoidan from Laminaria hyperborea with Natural Functions of the Retinal Pigment Epithelium
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Anti-inflammatory properties of antiangiogenic fucoidan in retinal pigment epithelium cells
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Comparison of the Effects of Fucoidans on the Cell Viability of Tumor and Non-Tumor Cell Lines
por: Bittkau, Kaya Saskia, et al.
Publicado: (2019)

Fucoidans as Potential Therapeutics for Age-Related Macular Degeneration—Current Evidence from In Vitro Research
por: Dörschmann, Philipp, et al.
Publicado: (2020)

Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Effects of Crude Fucus distichus Subspecies evanescens Fucoidan Extract on Retinal Pigment Epithelium Cells―Implications for Use in Age-Related Macular Degeneration
por: Rohwer, Kevin, et al.
Publicado: (2019)

Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight
por: Dörschmann, Philipp, et al.
Publicado: (2019)

Enzyme-Assisted Fucoidan Extraction from Brown Macroalgae Fucus distichus subsp. evanescens and Saccharina latissima
por: Nguyen, Thuan Thi, et al.
Publicado: (2020)

Evaluation of the Effects of Fucoidans from Fucus Species and Laminaria hyperborea against Oxidative Stress and Iron-Dependent Cell Death
por: Dörschmann, Philipp, et al.
Publicado: (2021)

Pro-inflammatory activation changes intracellular transport of bevacizumab in the retinal pigment epithelium in vitro
por: Hildebrandt, Julia, et al.
Publicado: (2021)

Fucoidan Reduces Secretion and Expression of Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium and Reduces Angiogenesis In Vitro
por: Dithmer, Michaela, et al.
Publicado: (2014)

Effect of Enzymatically Extracted Fucoidans on Angiogenesis and Osteogenesis in Primary Cell Culture Systems Mimicking Bone Tissue Environment
por: Ohmes, Julia, et al.
Publicado: (2020)

Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion
por: Kirsten, Nora, et al.
Publicado: (2023)

Evaluation of a Brown Seaweed Extract from Dictyosiphon foeniculaceus as a Potential Therapeutic Agent for the Treatment of Glioblastoma and Uveal Melanoma
por: Dörschmann, Philipp, et al.
Publicado: (2020)

Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines
por: Dithmer, Michaela, et al.
Publicado: (2017)

The Endo-α(1,3)-Fucoidanase Mef2 Releases Uniquely Branched Oligosaccharides from Saccharina latissima Fucoidans
por: Tran, Vy Ha Nguyen, et al.
Publicado: (2022)

Fucoidan as a Potential Therapeutic for Major Blinding Diseases—A Hypothesis
por: Klettner, Alexa
Publicado: (2016)

Retinal Pigment Epithelium Expressed Toll-like Receptors and Their Potential Role in Age-Related Macular Degeneration
por: Klettner, Alexa, et al.
Publicado: (2021)

Basolateral activation with TLR agonists induces polarized cytokine release and reduces barrier function in RPE in vitro
por: Terheyden, Laura, et al.
Publicado: (2020)

A novel thermostable prokaryotic fucoidan active sulfatase PsFucS1 with an unusual quaternary hexameric structure
por: Mikkelsen, Maria Dalgaard, et al.
Publicado: (2021)

The Endo-α(1,4) Specific Fucoidanase Fhf2 From Formosa haliotis Releases Highly Sulfated Fucoidan Oligosaccharides
por: Trang, Vo Thi Dieu, et al.
Publicado: (2022)

Regulation of constitutive vascular endothelial growth factor secretion in retinal pigment epithelium/choroid organ cultures: p38, nuclear factor kappaB, and the vascular endothelial growth factor receptor-2/phosphatidylinositol 3 kinase pathway
por: Klettner, Alexa, et al.
Publicado: (2013)

The Influence of Melatonin and Light on VEGF Secretion in Primary RPE Cells
por: Klettner, Alexa, et al.
Publicado: (2021)

Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE
por: Klettner, Alexa, et al.
Publicado: (2015)

Emulsified silicone oil is taken up by and induces pro-inflammatory response in primary retinal microglia
por: Klettner, Alexa, et al.
Publicado: (2020)

Modulation of inflammatory processes by thermal stimulating and RPE regenerative laser therapies in age related macular degeneration mouse models
por: Richert, Elisabeth, et al.
Publicado: (2020)

Properties of Cephalopod Skin Ommochromes to Inhibit Free Radicals, and the Maillard Reaction and Retino-Protective Mechanisms in Cellular Models Concerning Oxidative Stress, Angiogenesis, and Inflammation
por: Lewis, Luján Lidianys María, et al.
Publicado: (2022)

Novel Enzyme Actions for Sulphated Galactofucan Depolymerisation and a New Engineering Strategy for Molecular Stabilisation of Fucoidan Degrading Enzymes
por: Cao, Hang T. T., et al.
Publicado: (2018)

Selective retina therapy and thermal stimulation of the retina: different regenerative properties - implications for AMD therapy
por: Richert, Elisabeth, et al.
Publicado: (2021)

Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models
por: Tode, Jan, et al.
Publicado: (2018)

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models
por: Tode, Jan, et al.
Publicado: (2019)

Structural Characterization and Cytotoxic Activity Evaluation of Ulvan Polysaccharides Extracted from the Green Algae Ulva papenfussii
por: Tran, Vy Ha Nguyen, et al.
Publicado: (2023)

Important Determinants for Fucoidan Bioactivity: A Critical Review of Structure-Function Relations and Extraction Methods for Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds
por: Ale, Marcel Tutor, et al.
Publicado: (2011)

Structural and functional characterization of the novel endo-α(1,4)-fucoidanase Mef1 from the marine bacterium Muricauda eckloniae
por: Mikkelsen, Maria Dalgaard, et al.
Publicado: (2023)

Vascular Occlusions following Ocular Surgical Procedures: A Clinical Observation of Vascular Complications after Ocular Surgery
por: Fischer, Charlotte, et al.
Publicado: (2017)

Enzyme-Aided Extraction of Fucoidan by AMG Augments the Functionality of EPCs through Regulation of the AKT/Rheb Signaling Pathway
por: Rethineswaran, Vinoth Kumar, et al.
Publicado: (2019)

The Effects of Sargassum horneri Extract and Fucoidan on Tear Hyposecretion and Ocular Surface Injury in Rats with Dry Eye Diseases
por: Park, Su-Bin, et al.
Publicado: (2023)

Fucoidan Extracts Ameliorate Acute Colitis
por: Lean, Qi Ying, et al.
Publicado: (2015)

Extraction of Fucoidan from Turbinaria decurrens and the Synthesis of Fucoidan-Coated AgNPs for Anticoagulant Application
por: Shanthi, Nagarajan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hcit8fi29fi529me571arvbjmv