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In Silico Study of the Mechanism of Binding of the N-Terminal Region of α Synuclein to Synaptic-Like Membranes

The membrane binding by α-synuclein (αS), a presynaptic protein whose aggregation is strongly linked with Parkinson’s disease, influences its biological behavior under functional and pathological conditions. This interaction requires a conformational transition from a disordered-unbound to a partial...

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Detalles Bibliográficos
Autores principales:	Navarro-Paya, Carlos, Sanz-Hernandez, Maximo, De Simone, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344899/ https://www.ncbi.nlm.nih.gov/pubmed/32604928 http://dx.doi.org/10.3390/life10060098

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