Copolymeric Micelles Overcome the Oral Delivery Challenges of Amphotericin B

Classified as a Biopharmaceutical Classification System (BCS) class IV drug, amphotericin B (AmB) has low aqueous solubility and low permeability leading to low oral bioavailability. To improve these limitations, this study investigated the potential of AmB-loaded polymeric micelles (AmB-PM) to incr...

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Detalles Bibliográficos
Autores principales: Nimtrakul, Pataranapa, Williams, Desmond B., Tiyaboonchai, Waree, Prestidge, Clive A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344903/
https://www.ncbi.nlm.nih.gov/pubmed/32545189
http://dx.doi.org/10.3390/ph13060121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344903/
https://www.ncbi.nlm.nih.gov/pubmed/32545189
http://dx.doi.org/10.3390/ph13060121

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