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Copolymeric Micelles Overcome the Oral Delivery Challenges of Amphotericin B
Classified as a Biopharmaceutical Classification System (BCS) class IV drug, amphotericin B (AmB) has low aqueous solubility and low permeability leading to low oral bioavailability. To improve these limitations, this study investigated the potential of AmB-loaded polymeric micelles (AmB-PM) to incr...
Autores principales: | Nimtrakul, Pataranapa, Williams, Desmond B., Tiyaboonchai, Waree, Prestidge, Clive A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344903/ https://www.ncbi.nlm.nih.gov/pubmed/32545189 http://dx.doi.org/10.3390/ph13060121 |
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