A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors

Protein ubiquitinations play pivotal roles in many cellular processes, including homeostasis, responses to various stimulations, and progression of diseases. Deubiquitinating enzymes (DUBs) remove ubiquitin molecules from ubiquitinated proteins and cleave the polyubiquitin chain, thus negatively reg...

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Detalles Bibliográficos
Autores principales: Takahashi, Hirotaka, Yamanaka, Satoshi, Kuwada, Shohei, Higaki, Kana, Kido, Kohki, Sato, Yusuke, Fukai, Shuya, Tokunaga, Fuminori, Sawasaki, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344921/
https://www.ncbi.nlm.nih.gov/pubmed/32512835
http://dx.doi.org/10.3390/biomedicines8060152

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