Cargando…
Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model
Hot flushes are best-known for affecting menopausal women, but men who undergo life-saving castration due to androgen-sensitive prostate cancer also suffer from these vasomotor symptoms. Estrogen deficiency in these patients is a direct consequence of androgen deprivation, because estrogens (notably...
Autores principales: | Merchenthaler, Istvan, Lane, Malcolm, Stennett, Christina, Zhan, Min, Nguyen, Vien, Prokai-Tatrai, Katalin, Prokai, Laszlo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344942/ https://www.ncbi.nlm.nih.gov/pubmed/32531919 http://dx.doi.org/10.3390/ph13060119 |
Ejemplares similares
-
SUN-234 Brain-Selective Estrogen Therapy to Prevent Androgen Deprivation Therapy-Related Hot Flushes
por: Merchenthaler, Istvan, et al.
Publicado: (2020) -
Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery
por: Merchenthaler, Istvan, et al.
Publicado: (2016) -
A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019) -
[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021) -
Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications
por: Prokai, Laszlo, et al.
Publicado: (2021)