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Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance

Despite the widespread use of antibodies in clinical applications, the precise molecular mechanisms underlying antibody–antigen (Ab–Ag) interactions are often poorly understood. In this study, we exploit the technical features of a typical surface plasmon resonance (SPR) biosensor to dissect the kin...

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Detalles Bibliográficos
Autores principales: Guardiola, Salvador, Varese, Monica, Taulés, Marta, Díaz-Lobo, Mireia, García, Jesús, Giralt, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344977/
https://www.ncbi.nlm.nih.gov/pubmed/32604841
http://dx.doi.org/10.3390/ph13060134