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Group Testing-Based Robust Algorithm for Diagnosis of COVID-19

At the time of writing, the COVID-19 infection is spreading rapidly. Currently, there is no vaccine or treatment, and researchers around the world are attempting to fight the infection. In this paper, we consider a diagnosis method for COVID-19, which is characterized by a very rapid rate of infecti...

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Autor principal: Seong, Jin-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345105/
https://www.ncbi.nlm.nih.gov/pubmed/32545224
http://dx.doi.org/10.3390/diagnostics10060396
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author Seong, Jin-Taek
author_facet Seong, Jin-Taek
author_sort Seong, Jin-Taek
collection PubMed
description At the time of writing, the COVID-19 infection is spreading rapidly. Currently, there is no vaccine or treatment, and researchers around the world are attempting to fight the infection. In this paper, we consider a diagnosis method for COVID-19, which is characterized by a very rapid rate of infection and is widespread. A possible method for avoiding severe infections is to stop the spread of the infection in advance by the prompt and accurate diagnosis of COVID-19. To this end, we exploit a group testing (GT) scheme, which is used to find a small set of confirmed cases out of a large population. For the accurate detection of false positives and negatives, we propose a robust algorithm (RA) based on the maximum a posteriori probability (MAP). The key idea of the proposed RA is to exploit iterative detection to propagate beliefs to neighbor nodes by exchanging marginal probabilities between input and output nodes. As a result, we show that our proposed RA provides the benefit of being robust against noise in the GT schemes. In addition, we demonstrate the performance of our proposal with a number of tests and successfully find a set of infected samples in both noiseless and noisy GT schemes with different COVID-19 incidence rates.
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spelling pubmed-73451052020-07-09 Group Testing-Based Robust Algorithm for Diagnosis of COVID-19 Seong, Jin-Taek Diagnostics (Basel) Article At the time of writing, the COVID-19 infection is spreading rapidly. Currently, there is no vaccine or treatment, and researchers around the world are attempting to fight the infection. In this paper, we consider a diagnosis method for COVID-19, which is characterized by a very rapid rate of infection and is widespread. A possible method for avoiding severe infections is to stop the spread of the infection in advance by the prompt and accurate diagnosis of COVID-19. To this end, we exploit a group testing (GT) scheme, which is used to find a small set of confirmed cases out of a large population. For the accurate detection of false positives and negatives, we propose a robust algorithm (RA) based on the maximum a posteriori probability (MAP). The key idea of the proposed RA is to exploit iterative detection to propagate beliefs to neighbor nodes by exchanging marginal probabilities between input and output nodes. As a result, we show that our proposed RA provides the benefit of being robust against noise in the GT schemes. In addition, we demonstrate the performance of our proposal with a number of tests and successfully find a set of infected samples in both noiseless and noisy GT schemes with different COVID-19 incidence rates. MDPI 2020-06-11 /pmc/articles/PMC7345105/ /pubmed/32545224 http://dx.doi.org/10.3390/diagnostics10060396 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Seong, Jin-Taek
Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title_full Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title_fullStr Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title_full_unstemmed Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title_short Group Testing-Based Robust Algorithm for Diagnosis of COVID-19
title_sort group testing-based robust algorithm for diagnosis of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345105/
https://www.ncbi.nlm.nih.gov/pubmed/32545224
http://dx.doi.org/10.3390/diagnostics10060396
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