Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints
Due to the limits of computational time and computer memory, topology optimization problems involving fluidic flow frequently use simplified 2D models. Extruded versions of the 2D optimized results typically comprise the 3D designs to be fabricated. In practice, the depth of the fabricated flow chan...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345215/ https://www.ncbi.nlm.nih.gov/pubmed/32599820 http://dx.doi.org/10.3390/mi11060613 |
_version_ | 1783556128829865984 |
---|---|
author | Guo, Yuchen Pan, Hui Wadbro, Eddie Liu, Zhenyu |
author_facet | Guo, Yuchen Pan, Hui Wadbro, Eddie Liu, Zhenyu |
author_sort | Guo, Yuchen |
collection | PubMed |
description | Due to the limits of computational time and computer memory, topology optimization problems involving fluidic flow frequently use simplified 2D models. Extruded versions of the 2D optimized results typically comprise the 3D designs to be fabricated. In practice, the depth of the fabricated flow channels is finite; the limited flow depth together with the no-slip condition potentially make the fluidic performance of the 3D model very different from that of the simplified 2D model. This discrepancy significantly limits the usefulness of performing topology optimization involving fluidic flow in 2D—at least if special care is not taken. Inspired by the electric circuit analogy method, we limit the widths of the microchannels in the 2D optimization process. To reduce the difference of fluidic performance between the 2D model and its 3D counterpart, we propose an applicable 2D optimization model, and ensure the manufacturability of the obtained layout, combinations of several morphology-mimicking filters impose maximum or minimum length scales on the solid phase or the fluidic phase. Two typical Lab-on-chip functional units, Tesla valve and fluidic channel splitter, are used to illustrate the validity of the proposed application of length scale control. |
format | Online Article Text |
id | pubmed-7345215 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73452152020-07-09 Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints Guo, Yuchen Pan, Hui Wadbro, Eddie Liu, Zhenyu Micromachines (Basel) Article Due to the limits of computational time and computer memory, topology optimization problems involving fluidic flow frequently use simplified 2D models. Extruded versions of the 2D optimized results typically comprise the 3D designs to be fabricated. In practice, the depth of the fabricated flow channels is finite; the limited flow depth together with the no-slip condition potentially make the fluidic performance of the 3D model very different from that of the simplified 2D model. This discrepancy significantly limits the usefulness of performing topology optimization involving fluidic flow in 2D—at least if special care is not taken. Inspired by the electric circuit analogy method, we limit the widths of the microchannels in the 2D optimization process. To reduce the difference of fluidic performance between the 2D model and its 3D counterpart, we propose an applicable 2D optimization model, and ensure the manufacturability of the obtained layout, combinations of several morphology-mimicking filters impose maximum or minimum length scales on the solid phase or the fluidic phase. Two typical Lab-on-chip functional units, Tesla valve and fluidic channel splitter, are used to illustrate the validity of the proposed application of length scale control. MDPI 2020-06-24 /pmc/articles/PMC7345215/ /pubmed/32599820 http://dx.doi.org/10.3390/mi11060613 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Guo, Yuchen Pan, Hui Wadbro, Eddie Liu, Zhenyu Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title | Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title_full | Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title_fullStr | Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title_full_unstemmed | Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title_short | Design Applicable 3D Microfluidic Functional Units Using 2D Topology Optimization with Length Scale Constraints |
title_sort | design applicable 3d microfluidic functional units using 2d topology optimization with length scale constraints |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345215/ https://www.ncbi.nlm.nih.gov/pubmed/32599820 http://dx.doi.org/10.3390/mi11060613 |
work_keys_str_mv | AT guoyuchen designapplicable3dmicrofluidicfunctionalunitsusing2dtopologyoptimizationwithlengthscaleconstraints AT panhui designapplicable3dmicrofluidicfunctionalunitsusing2dtopologyoptimizationwithlengthscaleconstraints AT wadbroeddie designapplicable3dmicrofluidicfunctionalunitsusing2dtopologyoptimizationwithlengthscaleconstraints AT liuzhenyu designapplicable3dmicrofluidicfunctionalunitsusing2dtopologyoptimizationwithlengthscaleconstraints |