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Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi

Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summa...

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Autores principales: Chakraborty, Tanmoy, Tóth, Renáta, Nosanchuk, Joshua D., Gácser, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345259/
https://www.ncbi.nlm.nih.gov/pubmed/32349384
http://dx.doi.org/10.3390/jof6020056
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author Chakraborty, Tanmoy
Tóth, Renáta
Nosanchuk, Joshua D.
Gácser, Attila
author_facet Chakraborty, Tanmoy
Tóth, Renáta
Nosanchuk, Joshua D.
Gácser, Attila
author_sort Chakraborty, Tanmoy
collection PubMed
description Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.
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spelling pubmed-73452592020-07-09 Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi Chakraborty, Tanmoy Tóth, Renáta Nosanchuk, Joshua D. Gácser, Attila J Fungi (Basel) Review Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens. MDPI 2020-04-27 /pmc/articles/PMC7345259/ /pubmed/32349384 http://dx.doi.org/10.3390/jof6020056 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chakraborty, Tanmoy
Tóth, Renáta
Nosanchuk, Joshua D.
Gácser, Attila
Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title_full Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title_fullStr Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title_full_unstemmed Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title_short Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
title_sort multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345259/
https://www.ncbi.nlm.nih.gov/pubmed/32349384
http://dx.doi.org/10.3390/jof6020056
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