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Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi
Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345259/ https://www.ncbi.nlm.nih.gov/pubmed/32349384 http://dx.doi.org/10.3390/jof6020056 |
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author | Chakraborty, Tanmoy Tóth, Renáta Nosanchuk, Joshua D. Gácser, Attila |
author_facet | Chakraborty, Tanmoy Tóth, Renáta Nosanchuk, Joshua D. Gácser, Attila |
author_sort | Chakraborty, Tanmoy |
collection | PubMed |
description | Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens. |
format | Online Article Text |
id | pubmed-7345259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73452592020-07-09 Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi Chakraborty, Tanmoy Tóth, Renáta Nosanchuk, Joshua D. Gácser, Attila J Fungi (Basel) Review Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens. MDPI 2020-04-27 /pmc/articles/PMC7345259/ /pubmed/32349384 http://dx.doi.org/10.3390/jof6020056 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chakraborty, Tanmoy Tóth, Renáta Nosanchuk, Joshua D. Gácser, Attila Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title | Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title_full | Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title_fullStr | Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title_full_unstemmed | Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title_short | Multicopper Oxidases in Saccharomyces cerevisiae and Human Pathogenic Fungi |
title_sort | multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345259/ https://www.ncbi.nlm.nih.gov/pubmed/32349384 http://dx.doi.org/10.3390/jof6020056 |
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