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New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease

Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of...

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Detalles Bibliográficos
Autores principales: Moll-Bernardes, Renata J., Rosado-de-Castro, Paulo Henrique, Camargo, Gabriel Cordeiro, Mendes, Fernanda Souza Nogueira Sardinha, Brito, Adriana S. X., Sousa, Andréa Silvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345269/
https://www.ncbi.nlm.nih.gov/pubmed/32397217
http://dx.doi.org/10.3390/tropicalmed5020074
Descripción
Sumario:Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies.