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New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease

Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of...

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Autores principales: Moll-Bernardes, Renata J., Rosado-de-Castro, Paulo Henrique, Camargo, Gabriel Cordeiro, Mendes, Fernanda Souza Nogueira Sardinha, Brito, Adriana S. X., Sousa, Andréa Silvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345269/
https://www.ncbi.nlm.nih.gov/pubmed/32397217
http://dx.doi.org/10.3390/tropicalmed5020074
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author Moll-Bernardes, Renata J.
Rosado-de-Castro, Paulo Henrique
Camargo, Gabriel Cordeiro
Mendes, Fernanda Souza Nogueira Sardinha
Brito, Adriana S. X.
Sousa, Andréa Silvestre
author_facet Moll-Bernardes, Renata J.
Rosado-de-Castro, Paulo Henrique
Camargo, Gabriel Cordeiro
Mendes, Fernanda Souza Nogueira Sardinha
Brito, Adriana S. X.
Sousa, Andréa Silvestre
author_sort Moll-Bernardes, Renata J.
collection PubMed
description Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies.
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spelling pubmed-73452692020-07-09 New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease Moll-Bernardes, Renata J. Rosado-de-Castro, Paulo Henrique Camargo, Gabriel Cordeiro Mendes, Fernanda Souza Nogueira Sardinha Brito, Adriana S. X. Sousa, Andréa Silvestre Trop Med Infect Dis Review Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies. MDPI 2020-05-08 /pmc/articles/PMC7345269/ /pubmed/32397217 http://dx.doi.org/10.3390/tropicalmed5020074 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Moll-Bernardes, Renata J.
Rosado-de-Castro, Paulo Henrique
Camargo, Gabriel Cordeiro
Mendes, Fernanda Souza Nogueira Sardinha
Brito, Adriana S. X.
Sousa, Andréa Silvestre
New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title_full New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title_fullStr New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title_full_unstemmed New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title_short New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
title_sort new imaging parameters to predict sudden cardiac death in chagas disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345269/
https://www.ncbi.nlm.nih.gov/pubmed/32397217
http://dx.doi.org/10.3390/tropicalmed5020074
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