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Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series
This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy. In these cases, rifampin was contraindicated secondary to drug–drug interactions with the patients’ chronic medications. Rifabutin therapy was...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345564/ https://www.ncbi.nlm.nih.gov/pubmed/32545793 http://dx.doi.org/10.3390/antibiotics9060326 |
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author | Doub, James B. Heil, Emily L. Ntem-Mensah, Afua Neeley, Renaldo Ching, Patrick R. |
author_facet | Doub, James B. Heil, Emily L. Ntem-Mensah, Afua Neeley, Renaldo Ching, Patrick R. |
author_sort | Doub, James B. |
collection | PubMed |
description | This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy. In these cases, rifampin was contraindicated secondary to drug–drug interactions with the patients’ chronic medications. Rifabutin therapy was well tolerated with no side effects. As well, no patients had recurrence of their staphylococcal infections. This case series shows that rifabutin can be a beneficial adjuvant therapy in Staphylococcus biofilm infections when drug–drug interactions limit the use of rifampin. |
format | Online Article Text |
id | pubmed-7345564 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73455642020-07-09 Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series Doub, James B. Heil, Emily L. Ntem-Mensah, Afua Neeley, Renaldo Ching, Patrick R. Antibiotics (Basel) Case Report This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy. In these cases, rifampin was contraindicated secondary to drug–drug interactions with the patients’ chronic medications. Rifabutin therapy was well tolerated with no side effects. As well, no patients had recurrence of their staphylococcal infections. This case series shows that rifabutin can be a beneficial adjuvant therapy in Staphylococcus biofilm infections when drug–drug interactions limit the use of rifampin. MDPI 2020-06-13 /pmc/articles/PMC7345564/ /pubmed/32545793 http://dx.doi.org/10.3390/antibiotics9060326 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Doub, James B. Heil, Emily L. Ntem-Mensah, Afua Neeley, Renaldo Ching, Patrick R. Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title | Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title_full | Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title_fullStr | Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title_full_unstemmed | Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title_short | Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series |
title_sort | rifabutin use in staphylococcus biofilm infections: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345564/ https://www.ncbi.nlm.nih.gov/pubmed/32545793 http://dx.doi.org/10.3390/antibiotics9060326 |
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