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Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications

Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this re...

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Detalles Bibliográficos
Autores principales: Hughes, Robert M., Virag, Jitka A.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345574/
https://www.ncbi.nlm.nih.gov/pubmed/32492868
http://dx.doi.org/10.3390/ph13060112
Descripción
Sumario:Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this review briefly addresses what is currently known and being investigated in order to highlight the gaps and possible avenues for further investigation to capitalize on their diverse potential.