Cargando…

Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization

Inflammation and fibrosis induced by hyperglycemia are considered to play a critical role in the pathogenesis of diabetic nephropathy. As macrophage polarization may determine the severity and progression of inflammation, regulation of macrophage polarization may be an effective method to treat diab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Fajiang, Lei, Jiesen, Ran, Maoxia, Li, Yan, Deng, Li, Feng, Jian, Zhong, Yi, Li, Jiafu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345603/ https://www.ncbi.nlm.nih.gov/pubmed/32685556 http://dx.doi.org/10.1155/2020/4126913

Ejemplares similares

Hydrochloride fasudil attenuates brain injury in ICH rats
por: Li, Limin, et al.
Publicado: (2020)

Targeting the Shift from M1 to M2 Macrophages in Experimental Autoimmune Encephalomyelitis Mice Treated with Fasudil
por: Liu, Chunyun, et al.
Publicado: (2013)

Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
por: Li, Xueling, et al.
Publicado: (2020)

Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Jiang, Chunguo, et al.
Publicado: (2012)

Roles and crosstalks of macrophages in diabetic nephropathy
por: Li, Hai-Di, et al.
Publicado: (2022)

Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice
por: Chen, Xiaochen, et al.
Publicado: (2018)

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease
por: Tatenhorst, Lars, et al.
Publicado: (2016)

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage
por: Arita, Ryoichi, et al.
Publicado: (2009)

GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy
por: Li, Xiaohui, et al.
Publicado: (2023)

Effect of Fasudil on remyelination following cuprizone‐induced demyelination
por: Wang, Jing, et al.
Publicado: (2019)

Metabolomics study of fasudil on cisplatin-induced kidney injury
por: Xia, Demeng, et al.
Publicado: (2019)

Macrophage polarization in diabetic wound healing
por: Wu, Xingqian, et al.
Publicado: (2022)

ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion
por: Li, Hailing, et al.
Publicado: (2012)

Macrophage Phenotype and Fibrosis in Diabetic Nephropathy
por: Calle, Priscila, et al.
Publicado: (2020)

β-Sitosterol modulates macrophage polarization and attenuates rheumatoid inflammation in mice
por: Liu, Rui, et al.
Publicado: (2019)

Macrophage/microglia polarization for the treatment of diabetic retinopathy
por: Yao, Yujia, et al.
Publicado: (2023)

Identification of Fibrotic Biomarkers Associated with Macrophages in Diabetic Nephropathy
por: Hou, Rongrong, et al.
Publicado: (2023)

Retraction: Effect of Fasudil on remyelination following cuprizone‐induced demyelination.
por: Wang, Jing, et al.
Publicado: (2020)

The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy
por: Ma, Yanli, et al.
Publicado: (2023)

Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice
por: Albrecht, Thomas, et al.
Publicado: (2017)

Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis
por: Liu, Chunyun, et al.
Publicado: (2023)

Intravitreal Fasudil Combined with Bevacizumab for Treatment of Refractory Diabetic Macular Edema; a Pilot Study
por: Nourinia, Ramin, et al.
Publicado: (2013)

A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model
por: Fan, Xinhui, et al.
Publicado: (2022)

Therapeutic potentials of fasudil in liver fibrosis
por: Xi, Yue, et al.
Publicado: (2021)

Effects of rosuvastatin combined with fasudil therapy on rabbits with dyslipidemia
por: Li, Zhiming, et al.
Publicado: (2015)

Quercetin Attenuates Podocyte Apoptosis of Diabetic Nephropathy Through Targeting EGFR Signaling
por: Liu, Yiqi, et al.
Publicado: (2022)

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
por: Hou, Xiao-lin, et al.
Publicado: (2015)

STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy
por: Jiao, Baihai, et al.
Publicado: (2021)

Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases
por: Wang, Qing, et al.
Publicado: (2022)

Effect of fasudil on cognitive function following status convulsion in rats
por: He, Rong, et al.
Publicado: (2017)

Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress
por: Wang, Zeng Si, et al.
Publicado: (2015)

Deficiency of C3a receptor attenuates the development of diabetic nephropathy
por: Li, Xiao-Qian, et al.
Publicado: (2019)

Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice
por: Zeng, Peng, et al.
Publicado: (2015)

Fasudil Increased the Sensitivity to Gefitinib in NSCLC by Decreasing Intracellular Lipid Accumulation
por: Liao, Tingting, et al.
Publicado: (2022)

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
por: Gil, Natali, et al.
Publicado: (2012)

Resveratrol Attenuates Diabetic Nephropathy via Modulating Angiogenesis
por: Wen, Donghai, et al.
Publicado: (2013)

Effects of autophagy on macrophage adhesion and migration in diabetic nephropathy
por: Jiang, Yuteng, et al.
Publicado: (2019)

Fasudil combined with methylcobalamin or lipoic acid can improve the nerve conduction velocity in patients with diabetic peripheral neuropathy: A meta-analysis
por: Jiang, De-Qi, et al.
Publicado: (2018)

Effects of fasudil on blood–brain barrier integrity
por: Sato, Kei, et al.
Publicado: (2022)

Lupeol reduces M1 macrophage polarization to attenuate immunologic dissonance and fatty acid deposition in rats with diet-induced metabolic syndrome
por: Li, Jin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5818g2f2gb5r9htbumd9402g29