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Identification of Time-Invariant Biomarkers for Non-Genotoxic Hepatocarcinogen Assessment
Non-genotoxic hepatocarcinogens (NGHCs) can only be confirmed by 2-year rodent studies. Toxicogenomics (TGx) approaches using gene expression profiles from short-term animal studies could enable early assessment of NGHCs. However, high variance in the modulation of the genes had been noted among exp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345770/ https://www.ncbi.nlm.nih.gov/pubmed/32560183 http://dx.doi.org/10.3390/ijerph17124298 |