MSH2 Overexpression Due to an Unclassified Variant in 3’-Untranslated Region in a Patient with Colon Cancer

Background: The loss or low expression of DNA mismatch repair (MMR) genes can result in genomic instability and tumorigenesis. One such gene, MSH2, is mutated or rearranged in Lynch syndrome (LS), which is characterized by a high risk of tumor development, including colorectal cancer. However, many...

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Detalles Bibliográficos
Autores principales: Liccardo, Raffaella, Nolano, Antonio, Lambiase, Matilde, Della Ragione, Carlo, De Rosa, Marina, Izzo, Paola, Duraturo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345785/
https://www.ncbi.nlm.nih.gov/pubmed/32575404
http://dx.doi.org/10.3390/biomedicines8060167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345785/
https://www.ncbi.nlm.nih.gov/pubmed/32575404
http://dx.doi.org/10.3390/biomedicines8060167

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