Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

SARS-CoV-2 Spike protein was predicted by molecular docking to bind the host cell surface GRP78, which was suggested as a putative good molecular target to inhibit Covid-19. We aimed to confirm that GRP78 gene expression was increased in blood of SARS-CoV-2 (+) versus SARS-CoV-2 (−) pneumonia patien...

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Detalles Bibliográficos
Autores principales: Palmeira, Andreia, Sousa, Emília, Köseler, Aylin, Sabirli, Ramazan, Gören, Tarık, Türkçüer, İbrahim, Kurt, Özgür, Pinto, Madalena M., Vasconcelos, M. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345920/
https://www.ncbi.nlm.nih.gov/pubmed/32630514
http://dx.doi.org/10.3390/ph13060132

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