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CHK2 is essential for spindle assembly and DNA repair during the first cleavage of mouse embryos

The quality of the early embryo is critical for embryonic development and implantation. Errors during cleavage lead to aneuploidy in embryos. As a cell cycle checkpoint protein, CHK2 participates in DNA replication, cell cycle arrest and spindle assembly. However, the functions of CHK2 in early deve...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Han, Li, Wen-Jing, Ju, Jia-Qian, Pan, Meng-Hao, Xu, Yao, Sun, Ming-Hong, Li, Mo, Sun, Shao-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346029/
https://www.ncbi.nlm.nih.gov/pubmed/32484784
http://dx.doi.org/10.18632/aging.103267

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