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CHK2 is essential for spindle assembly and DNA repair during the first cleavage of mouse embryos
The quality of the early embryo is critical for embryonic development and implantation. Errors during cleavage lead to aneuploidy in embryos. As a cell cycle checkpoint protein, CHK2 participates in DNA replication, cell cycle arrest and spindle assembly. However, the functions of CHK2 in early deve...
Autores principales: | Li, Xiao-Han, Li, Wen-Jing, Ju, Jia-Qian, Pan, Meng-Hao, Xu, Yao, Sun, Ming-Hong, Li, Mo, Sun, Shao-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346029/ https://www.ncbi.nlm.nih.gov/pubmed/32484784 http://dx.doi.org/10.18632/aging.103267 |
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