Cargando…

Dynamic changes of autophagic flux induced by Abeta in the brain of postmortem Alzheimer’s disease patients, animal models and cell models

Autophagy has been reported to play a dual "double-edged sword" role in the occurrence and development of Alzheimer’s disease (AD). To assess the relationship between AD and autophagy, the dynamic changes of autophagic flux in the brain of postmortem AD patients, animal models and cell mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Long, Zhimin, Chen, Jingfei, Zhao, Yueyang, Zhou, Wen, Yao, Qiuhui, Wang, Yingxiong, He, Guiqiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346050/ https://www.ncbi.nlm.nih.gov/pubmed/32535554 http://dx.doi.org/10.18632/aging.103305

Ejemplares similares

Effects of ovarian hormone loss on neuritic plaques and autophagic flux in the brains of adult female APP/PS1 double-transgenic mice
por: Yao, Qiuhui, et al.
Publicado: (2018)

Valproic Acid Stimulates Hippocampal Neurogenesis via Activating the Wnt/β-Catenin Signaling Pathway in the APP/PS1/Nestin-GFP Triple Transgenic Mouse Model of Alzheimer’s Disease
por: Zeng, Qinghua, et al.
Publicado: (2019)

Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X
por: Antonios, Gregory, et al.
Publicado: (2015)

Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila
por: Ling, Daijun, et al.
Publicado: (2009)

Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease
por: Thijssen, Elisabeth H., et al.
Publicado: (2021)

Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer’s Disease
por: Zhou, Wen, et al.
Publicado: (2021)

Is abeta a sufficient biomarker for monitoring anti-abeta clinical studies? A critical review
por: Moreth, Jens, et al.
Publicado: (2013)

Site specific NMR characterization of abeta-40 oligomers cross seeded by abeta-42 oligomers
por: Chang, Han-Wen, et al.
Publicado: (2022)

Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42
por: Dietrich, Katharina, et al.
Publicado: (2018)

Phagocytosis of Candida albicans Inhibits Autophagic Flux in Macrophages
por: Duan, Zhimin, et al.
Publicado: (2018)

Melatonin and Abeta, Macular Degeneration and Alzheimers Disease: Same Disease, Different Outcomes?
por: Vladan, Bajic, et al.
Publicado: (2012)

Systemic Administration of Abeta mAb Reduces Retinal Deposition of Abeta and Activated Complement C3 in Age-Related Macular Degeneration Mouse Model
por: Catchpole, Ian, et al.
Publicado: (2013)

Mannan-Abeta(28 )conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice
por: Petrushina, Irina, et al.
Publicado: (2008)

Autophagic flux is impaired in the brain tissue of Tay-Sachs disease mouse model
por: Sengul, Tugce, et al.
Publicado: (2023)

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse
por: Takamura, Ayumi, et al.
Publicado: (2011)

Using cultured canine cardiac slices to model the autophagic flux with doxorubicin
por: Boukhalfa, Asma, et al.
Publicado: (2023)

Intestinal changes in permeability, tight junction and mucin synthesis in a mouse model of Alzheimer's disease
por: He, Jing, et al.
Publicado: (2023)

The Precision Control of Autophagic Flux and Vesicle Dynamics—A Micropattern Approach
por: du Toit, André, et al.
Publicado: (2018)

Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics
por: Miyazaki, Masaya, et al.
Publicado: (2021)

Saliva levels of Abeta1-42 as potential biomarker of Alzheimer's disease: a pilot study
por: Bermejo-Pareja, Felix, et al.
Publicado: (2010)

Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia
por: Sullivan, Courtney R., et al.
Publicado: (2019)

Are animal models predictive for human postmortem muscle protein degradation?
por: Ehrenfellner, Bianca, et al.
Publicado: (2017)

Acute Blast Injury Reduces Brain Abeta in Two Rodent Species
por: De Gasperi, Rita, et al.
Publicado: (2012)

Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates
por: Maulucci, Giuseppe, et al.
Publicado: (2015)

Potential sources of interference on Abeta immunoassays in biological samples
por: Vanderstichele, Hugo, et al.
Publicado: (2012)

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases
por: Wirths, Oliver, et al.
Publicado: (2009)

Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease
por: Bayer, Thomas A., et al.
Publicado: (2014)

The pros and cons of autophagic flux among herpesviruses
por: Grose, Charles, et al.
Publicado: (2015)

Using enhanced-mitophagy to measure autophagic flux
por: Baudot, Alice D., et al.
Publicado: (2015)

Autophagic flux response and glioblastoma sensitivity to radiation
por: Mitrakas, Achilleas G., et al.
Publicado: (2018)

Small fluorescent molecules for monitoring autophagic flux
por: Iwashita, Hidefumi, et al.
Publicado: (2018)

Interleukin-4 affects microglial autophagic flux
por: Tang, Run-Hong, et al.
Publicado: (2019)

Surgical procedures suppress autophagic flux in the kidney
por: Brown, Carolyn N., et al.
Publicado: (2021)

Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome
por: Follo, Carlo, et al.
Publicado: (2016)

Diosmin Inhibits Glioblastoma Growth through Inhibition of Autophagic Flux
por: Chang, Yung-Lung, et al.
Publicado: (2021)

Dihydroartemisinin Ameliorates Learning and Memory in Alzheimer’s Disease Through Promoting Autophagosome-Lysosome Fusion and Autolysosomal Degradation for Aβ Clearance
por: Zhao, Yueyang, et al.
Publicado: (2020)

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology
por: Trujillo-Estrada, Laura, et al.
Publicado: (2013)

A Rat Model of Alzheimer’s Disease Based on Abeta(42) and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems
por: Petrasek, Tomas, et al.
Publicado: (2016)

Explore the Role of Abeta in Axonal Trafficking Deficits Induced by Alpha Synuclein in Parkinson Disease Mouse Model
por: Castro, Alfredo
Publicado: (2021)

Explore the Role of Abeta in Axonal Trafficking Deficits Induced by Alpha Synuclein in Parkinson Disease Mouse Model
por: Castro, Alfredo
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bld2lin2iij10bgvoun2j4stjd