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Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways
Liver fibrosis is the reversible deposition of extracellular matrix (ECM) and scar formation after liver damage by various stimuli. The interaction between NOX4/ROS and RhoA/ROCK1 in liver fibrosis is not yet clear. Ursolic acid (UA) is a traditional Chinese medicine with anti-fibrotic effects, but...
Autores principales: | Wan, Sizhe, Luo, Fangyun, Huang, Chenkai, Liu, Cong, Luo, Qingtian, Zhu, Xuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346053/ https://www.ncbi.nlm.nih.gov/pubmed/32496208 http://dx.doi.org/10.18632/aging.103282 |
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