T cell stimulation and expansion by SunTag-based clustering of anti-CD3/CD28 scFv

Therapeutic ex vivo T cell expansion is limited by low rates and poor functionality, especially for T cells from aged cancer patients. Here, we describe a novel method for T cell stimulation and expansion using a system named SunTag-based clustering of anti-CD3/CD28 scFv (SBCS). In this method, SunT...

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Detalles Bibliográficos
Autores principales: Zhong, Kunhong, Liu, Zhiyong, Li, Hongjian, Zhao, Shasha, Wang, Yuelong, Guo, Wenhao, Zheng, Xi, Yang, Hui, Guo, Gang, Zhou, Liangxue, Xu, Jianguo, Tong, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346064/
https://www.ncbi.nlm.nih.gov/pubmed/32526703
http://dx.doi.org/10.18632/aging.103318

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