Isosamidin from Peucedanum japonicum Roots Prevents Methylglyoxal-Induced Glucotoxicity in Human Umbilical Vein Endothelial Cells via Suppression of ROS-Mediated Bax/Bcl-2

Methylglyoxal (MGO) is a highly reactive metabolite of glucose. Elevated levels of MGO induce the generation of reactive oxygen species (ROS) and cause cell death in endothelial cells. Vascular endothelial cell damage by ROS has been implicated in the progression of diabetic vascular complications,...

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Detalles Bibliográficos
Autores principales: Do, Moon Ho, Lee, Jae Hyuk, Ahn, Jongmin, Hong, Min Jee, Kim, Jinwoong, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346203/
https://www.ncbi.nlm.nih.gov/pubmed/32560521
http://dx.doi.org/10.3390/antiox9060531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346203/
https://www.ncbi.nlm.nih.gov/pubmed/32560521
http://dx.doi.org/10.3390/antiox9060531

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