Cargando…

Cathepsin K Deficiency Impaired Ischemia-Induced Neovascularization in Aged Mice

BACKGROUND: Aging is a major risk factor for cardiovascular disease. Cysteine protease cathepsin K (CatK) has been implicated in the process of angiogenesis, but the exact roles of individual CatK in vessel formation during aging are poorly understood. METHODS AND RESULTS: To study the putative role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yue, Xueling, Jiang, Haiying, Xu, Ying, Xia, Manli, Cheng, Xian-Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346230/ https://www.ncbi.nlm.nih.gov/pubmed/32676120 http://dx.doi.org/10.1155/2020/6938620

Ejemplares similares

Cathepsin K Deficiency Prevented Kidney Damage and Dysfunction in Response to 5/6 Nephrectomy Injury in Mice With or Without Chronic Stress
por: Yue, Xueling, et al.
Publicado: (2022)

Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination
por: Meng, Xiangkun, et al.
Publicado: (2022)

Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
por: Tsukuba, Takayuki, et al.
Publicado: (2013)

Cathepsin S activity controls chronic stress-induced muscle atrophy and dysfunction in mice
por: Wan, Ying, et al.
Publicado: (2023)

Cathepsin S Deficiency Mitigated Chronic Stress–Related Neointimal Hyperplasia in Mice
por: Wang, Hailong, et al.
Publicado: (2019)

The Soluble VEGF Receptor sFlt-1 Contributes to Impaired Neovascularization in Aged Mice
por: Zhao, Guangxian, et al.
Publicado: (2017)

Increased Serum Cathepsin K in Patients with Coronary Artery Disease
por: Li, Xiang, et al.
Publicado: (2014)

Correction: Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
Publicado: (2014)

Advances in neovascularization after diabetic ischemia
por: Cai, Yue, et al.
Publicado: (2022)

Effects of STAT3 on aging-dependent neovascularization impairment following limb ischemia: from bedside to bench
por: Chang, Wei-Ting, et al.
Publicado: (2022)

Cathepsin K activity controls cardiotoxin‐induced skeletal muscle repair in mice
por: Ogasawara, Shinyu, et al.
Publicado: (2017)

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE(-/-) Mice
por: Donners, Marjo M. P. C., et al.
Publicado: (2016)

Cathepsin S are involved in human carotid atherosclerotic disease progression, mainly by mediating phagosomes: bioinformatics and in vivo and vitro experiments
por: Wang, Hailong, et al.
Publicado: (2022)

Increased Circulating Cathepsin K in Patients with Chronic Heart Failure
por: Zhao, Guangxian, et al.
Publicado: (2015)

The effect of cathepsin K deficiency on airway development and TGF-β1 degradation
por: Zhang, Dongwei, et al.
Publicado: (2011)

Cathepsin K knockout alleviates aging-induced cardiac dysfunction
por: Hua, Yinan, et al.
Publicado: (2015)

Zoledronate Inhibits Ischemia-Induced Neovascularization by Impairing the Mobilization and Function of Endothelial Progenitor Cells
por: Tsai, Shih-Hung, et al.
Publicado: (2012)

Cathepsin K deficiency in mice induces structural and metabolic changes in the central nervous system that are associated with learning and memory deficits
por: Dauth, Stephanie, et al.
Publicado: (2011)

Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice
por: Ueno, Daisuke, et al.
Publicado: (2023)

Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice
por: Winkeler, Crystal L., et al.
Publicado: (2012)

Cathepsin K knockout protects against cardiac dysfunction in diabetic mice
por: Guo, Rui, et al.
Publicado: (2017)

Regulation of Elastinolytic Cysteine Proteinase Activity in Normal and Cathepsin K–Deficient Human Macrophages
por: Punturieri, Antonello, et al.
Publicado: (2000)

Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling
por: Ni, Junjun, et al.
Publicado: (2021)

Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis
por: Iwama, Hideaki, et al.
Publicado: (2021)

Deletion of MicroRNA-21 Impairs Neovascularization Following Limb Ischemia: From Bedside to Bench
por: Chang, Wei-Ting, et al.
Publicado: (2022)

Neonatal exposure to high oxygen levels leads to impaired ischemia-induced neovascularization in adulthood
por: Mathieu, Raphael, et al.
Publicado: (2017)

Cathepsin K: The Action in and Beyond Bone
por: Dai, Rongchen, et al.
Publicado: (2020)

Telomerase deficiency delays renal recovery in mice after ischemia reperfusion injury by impairing autophagy
por: Cheng, Huifang, et al.
Publicado: (2015)

Palmitate impairs angiogenesis via suppression of cathepsin activity
por: Zhang, Jin, et al.
Publicado: (2017)

Gene Targeting of the Cysteine Peptidase Cathepsin H Impairs Lung Surfactant in Mice
por: Bühling, Frank, et al.
Publicado: (2011)

Critical Roles of Reactive Oxygen Species in Age-Related Impairment in Ischemia-Induced Neovascularization by Regulating Stem and Progenitor Cell Function
por: Lam, Yuen Ting
Publicado: (2016)

Accelerated Vascular Aging in CuZnSOD-Deficient Mice: Impact on EPC Function and Reparative Neovascularization
por: Groleau, Jessika, et al.
Publicado: (2011)

Multi-faceted roles of cathepsins in ischemia reperfusion injury (Review)
por: Huertas, Jaime, et al.
Publicado: (2022)

Zinc deficiency impairs ischemia-induced angiogenesis
por: Tsuruoka, Takuya, et al.
Publicado: (2021)

Induction of Premalignant Host Responses by Cathepsin X/Z-Deficiency in Helicobacter Pylori-Infected Mice
por: Krueger, Sabine, et al.
Publicado: (2013)

Can cysteinyl cathepsin activity control diet-induced NAFLD?
por: Yu, Chenglin, et al.
Publicado: (2020)

Cathepsin K induces platelet dysfunction and affects cell signaling in breast cancer - molecularly distinct behavior of cathepsin K in breast cancer
por: Andrade, Sheila Siqueira, et al.
Publicado: (2016)

Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway
por: Wu, Hongxian, et al.
Publicado: (2016)

Cathepsin K Null Mice Show Reduced Adiposity during the Rapid Accumulation of Fat Stores
por: Funicello, Marcella, et al.
Publicado: (2007)

Variations in Surgical Procedures for Inducing Hind Limb Ischemia in Mice and the Impact of These Variations on Neovascularization Assessment
por: Aref, Zeen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dm6t0udp7e6bp5o2papb0nm1us