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Innate immune responses to duck Tembusu virus infection

The disease caused by duck Tembusu virus (DTMUV) is characterized by severe egg-drop in laying ducks. Currently, the disease has spread to most duck-raising areas in China, leading to great economic losses in the duck industry. In the recent years, DTMUV has raised some concerns, because of its expa...

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Autores principales: Li, Ning, Zhao, Jun, Yang, Yudong, Zeng, Yongqing, Liu, Sidang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346331/
https://www.ncbi.nlm.nih.gov/pubmed/32641107
http://dx.doi.org/10.1186/s13567-020-00814-9
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author Li, Ning
Zhao, Jun
Yang, Yudong
Zeng, Yongqing
Liu, Sidang
author_facet Li, Ning
Zhao, Jun
Yang, Yudong
Zeng, Yongqing
Liu, Sidang
author_sort Li, Ning
collection PubMed
description The disease caused by duck Tembusu virus (DTMUV) is characterized by severe egg-drop in laying ducks. Currently, the disease has spread to most duck-raising areas in China, leading to great economic losses in the duck industry. In the recent years, DTMUV has raised some concerns, because of its expanding host range and increasing pathogenicity, as well as the potential threat to public health. Innate immunity is crucial for defending against invading pathogens in the early stages of infection. Recently, studies on the interaction between DTMUV and host innate immune response have made great progress. In the review, we provide an overview of DTMUV and summarize current advances in our understanding of the interaction between DTMUV and innate immunity, including the host innate immune responses to DTMUV infection through pattern recognition receptors (PRRs), signaling transducer molecules, interferon-stimulated genes (ISGs), and the immune evasion strategies employed by DTMUV. The aim of the review is to gain an in-depth understanding of DTMUV pathogenesis to facilitate future studies.
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spelling pubmed-73463312020-07-17 Innate immune responses to duck Tembusu virus infection Li, Ning Zhao, Jun Yang, Yudong Zeng, Yongqing Liu, Sidang Vet Res Review The disease caused by duck Tembusu virus (DTMUV) is characterized by severe egg-drop in laying ducks. Currently, the disease has spread to most duck-raising areas in China, leading to great economic losses in the duck industry. In the recent years, DTMUV has raised some concerns, because of its expanding host range and increasing pathogenicity, as well as the potential threat to public health. Innate immunity is crucial for defending against invading pathogens in the early stages of infection. Recently, studies on the interaction between DTMUV and host innate immune response have made great progress. In the review, we provide an overview of DTMUV and summarize current advances in our understanding of the interaction between DTMUV and innate immunity, including the host innate immune responses to DTMUV infection through pattern recognition receptors (PRRs), signaling transducer molecules, interferon-stimulated genes (ISGs), and the immune evasion strategies employed by DTMUV. The aim of the review is to gain an in-depth understanding of DTMUV pathogenesis to facilitate future studies. BioMed Central 2020-07-13 2020 /pmc/articles/PMC7346331/ /pubmed/32641107 http://dx.doi.org/10.1186/s13567-020-00814-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Li, Ning
Zhao, Jun
Yang, Yudong
Zeng, Yongqing
Liu, Sidang
Innate immune responses to duck Tembusu virus infection
title Innate immune responses to duck Tembusu virus infection
title_full Innate immune responses to duck Tembusu virus infection
title_fullStr Innate immune responses to duck Tembusu virus infection
title_full_unstemmed Innate immune responses to duck Tembusu virus infection
title_short Innate immune responses to duck Tembusu virus infection
title_sort innate immune responses to duck tembusu virus infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346331/
https://www.ncbi.nlm.nih.gov/pubmed/32641107
http://dx.doi.org/10.1186/s13567-020-00814-9
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