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Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report

Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism o...

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Detalles Bibliográficos
Autores principales: Fryer, Vincent, Billings, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346334/
https://www.ncbi.nlm.nih.gov/pubmed/32656021
http://dx.doi.org/10.7759/cureus.8505
Descripción
Sumario:Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism of action, especially when used in combination with antidepressants. The following case highlights the importance of understanding the potential risks in prescribing quetiapine in patients who have underlying genetic susceptibility towards low white blood cell counts.