Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report

Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism o...

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Detalles Bibliográficos
Autores principales: Fryer, Vincent, Billings, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346334/
https://www.ncbi.nlm.nih.gov/pubmed/32656021
http://dx.doi.org/10.7759/cureus.8505
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author Fryer, Vincent
Billings, James
author_facet Fryer, Vincent
Billings, James
author_sort Fryer, Vincent
collection PubMed
description Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism of action, especially when used in combination with antidepressants. The following case highlights the importance of understanding the potential risks in prescribing quetiapine in patients who have underlying genetic susceptibility towards low white blood cell counts.
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spelling pubmed-73463342020-07-10 Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report Fryer, Vincent Billings, James Cureus Internal Medicine Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism of action, especially when used in combination with antidepressants. The following case highlights the importance of understanding the potential risks in prescribing quetiapine in patients who have underlying genetic susceptibility towards low white blood cell counts. Cureus 2020-06-08 /pmc/articles/PMC7346334/ /pubmed/32656021 http://dx.doi.org/10.7759/cureus.8505 Text en Copyright © 2020, Fryer et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Fryer, Vincent
Billings, James
Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title_full Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title_fullStr Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title_full_unstemmed Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title_short Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
title_sort low-dose quetiapine causing agranulocytosis and leucopenia in a patient with benign neutropenia: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346334/
https://www.ncbi.nlm.nih.gov/pubmed/32656021
http://dx.doi.org/10.7759/cureus.8505
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