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Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms
BACKGROUND: The change in the benzodiazepine (BZD) use of patients with medically unexplained symptoms (MUS) following the application of relaxation therapy were examined. METHODS: Of the 221 outpatients with MUS using BZD, 42 received relaxation therapy. Change in BZD use was compared using a relax...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346372/ https://www.ncbi.nlm.nih.gov/pubmed/32670396 http://dx.doi.org/10.1186/s13030-020-00187-7 |
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author | Hashimoto, Kazuaki Takeuchi, Takeaki Koyama, Akiko Hiiragi, Miki Suka, Shunsuke Hashizume, Masahiro |
author_facet | Hashimoto, Kazuaki Takeuchi, Takeaki Koyama, Akiko Hiiragi, Miki Suka, Shunsuke Hashizume, Masahiro |
author_sort | Hashimoto, Kazuaki |
collection | PubMed |
description | BACKGROUND: The change in the benzodiazepine (BZD) use of patients with medically unexplained symptoms (MUS) following the application of relaxation therapy were examined. METHODS: Of the 221 outpatients with MUS using BZD, 42 received relaxation therapy. Change in BZD use was compared using a relaxation group (n = 42) and a control group that had 84 MUS patients whose baseline was matched by optimal matching algorithms. Logistic regression analysis was done to evaluate the effect of BZD-dependent factors on the BZD dose of the relaxation group. RESULTS: Compared with the control group, the number of patients who decreased the amount of BZD and the number of patients whose subjective symptoms of MUS improved were significantly higher in the relaxation group (p < 0.05). In addition, a factor that made it difficult to reduce the BZD of MUS patients who had undergone relaxation was a long history of BZD use, for more than 6 months (odds ratio, 0.06, 95% confidence interval, 0.01–0.36). CONCLUSIONS: Relaxation therapy for patients with MUS may help reduce BZD use; however, early intervention is important to prevent BZD dependence. |
format | Online Article Text |
id | pubmed-7346372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73463722020-07-14 Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms Hashimoto, Kazuaki Takeuchi, Takeaki Koyama, Akiko Hiiragi, Miki Suka, Shunsuke Hashizume, Masahiro Biopsychosoc Med Research BACKGROUND: The change in the benzodiazepine (BZD) use of patients with medically unexplained symptoms (MUS) following the application of relaxation therapy were examined. METHODS: Of the 221 outpatients with MUS using BZD, 42 received relaxation therapy. Change in BZD use was compared using a relaxation group (n = 42) and a control group that had 84 MUS patients whose baseline was matched by optimal matching algorithms. Logistic regression analysis was done to evaluate the effect of BZD-dependent factors on the BZD dose of the relaxation group. RESULTS: Compared with the control group, the number of patients who decreased the amount of BZD and the number of patients whose subjective symptoms of MUS improved were significantly higher in the relaxation group (p < 0.05). In addition, a factor that made it difficult to reduce the BZD of MUS patients who had undergone relaxation was a long history of BZD use, for more than 6 months (odds ratio, 0.06, 95% confidence interval, 0.01–0.36). CONCLUSIONS: Relaxation therapy for patients with MUS may help reduce BZD use; however, early intervention is important to prevent BZD dependence. BioMed Central 2020-07-09 /pmc/articles/PMC7346372/ /pubmed/32670396 http://dx.doi.org/10.1186/s13030-020-00187-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Hashimoto, Kazuaki Takeuchi, Takeaki Koyama, Akiko Hiiragi, Miki Suka, Shunsuke Hashizume, Masahiro Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title | Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title_full | Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title_fullStr | Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title_full_unstemmed | Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title_short | Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
title_sort | effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346372/ https://www.ncbi.nlm.nih.gov/pubmed/32670396 http://dx.doi.org/10.1186/s13030-020-00187-7 |
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